Antiseptic mechanism of nano-sized electrostatic water molecules on SARS-CoV-2

When the envelope, protein, and RNA of SARS-CoV-2 are broken by small, nano-electrostatic water molecules, the virus is unable to bind to host cells. Credit score: College of Warwick

Present disinfection methods have important drawbacks, which is why the World Well being Group doesn’t suggest routine spraying or fogging of biocidal brokers, or UV sterilization, in occupied areas. One doable different is the nano-electrostatic water particles generated by the electrostatic sprayer developed by Panasonic. Water molecules include reactive oxygen species (ROS) that injury lipids, proteins, and DNA and are stated to purify many bacterial and viral species.

Assistant Professor Yasuji’s staff confirmed of their earlier analysis that the electrostatic nanoscale decomposes into atoms water molecules SARS-CoV-2 is cleared, however the mechanism has remained a thriller. Their new paper was revealed in Journal of Nanoparticle Analysis Describes the injury they noticed when SARS-CoV-2 was uncovered to nano-sized electrostatic water molecules.

The researchers confirmed that splashing water molecules decreased an infection of cells with SARS-CoV-2 whereas observing injury to the virus. “We noticed that nano-sized electrostatic water molecules broken the virus envelope, protein and RNA, rendering them unable to bind to host cells,” defined Affiliate Professor Yasuji.

“The phenomena we noticed are the principle mechanism by which small-sized electrostatic water molecules disinfect SARS-CoV-2, and we discovered that the goal of the water molecules just isn’t the precise construction of the viral or particular proteins. As a result of the water molecules have an effect on the viral envelope, protein and RNA, and should It additionally disinfects different encapsulated viral species.”

Whereas this proof of idea demonstrates how nano-sized electrostatic water molecules destroy SARS-CoV-2, the complete scope of its software stays unknown. “We don’t know precisely what agent destroys SARS-CoV-2; ROS in molecules could also be this issue as a result of ROS injury lipid, protein and DNA/RNA by way of oxidation. Furthermore, our research confirmed that water molecules purify SARS-CoV.” -2 on surfaces below closed experimental circumstances.However the effectiveness of nano-sized electrostatic water molecules can change relying on humidity, temperature, and so forth. environmental elements; For this technique to be sensible, it should work in lots of environments,” Affiliate Professor Yasuji concluded. Our future research will concentrate on the mechanism of motion of ROS and check whether or not electrostatic nano-sized water molecules are efficient in opposition to airborne SARS. -CoV-2. ”


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extra data:
Mayo Yasugi et al., Mechanisms underlying inactivation of SARS-CoV-2 by nano-sized electrostatic water molecules, Journal of Nanoparticle Analysis (2022). DOI: 10.1007/s11051-022-05485-5

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